BMC Structural Biology

Table 3 Predicted peptide-binding motifs for HLA class I alleles without sufficient binding data to make direct predictions.

From: A geometric and algebraic view of MHC-peptide complexes and their binding properties

Pp	Paa	A23	A26	A32	A34	A36	A43	A66	A68	A69	A74	B62	B75	B72	B63	B37	B61	B41	B46	B48	B49	B50	B52	B55	B57	B58	859	B67	B73	B78	B81
1	A		0.3	0.3	0.3	0.3	0.3	0.3	8.3	0.3	0.3				0.3										0.3	0.3
1	F		0.3		0.3			0.3	0.3	0.3		0.3	0.3	0.3	0.3		0.3	0.3	0.3	0.3			0.3	0-3	0.3	0.3	0.3	0,3	0,3	0,3	0,3
1	R	0.3	0.3	0.3	0.3		0.3	0.3			0.3	0.3	0.3	0.4	0.3	0.3	0.3	0.3	0.3	0.4	0.3	0.3	0,3	04	0.3	0.3	0.4	0.4	0.5	0.3	0.4
2	E						0.5					0.7	0.7	0.7		0.7	0.7	0.7		0.7	0.7	0.7	0.7
2	F	0.3
2	I	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3				0.3				0.3						0.3	0.3			0.3
2	L	0.5	0.5	0.5	0.5	0.5	0.5	0.5	0.5	0.5	0.5	0.5	0.5	0.5	0.5	0.5	0.4	0.5	0.5	0.4	0.5	0.5	0.3	0.3	0.5	0.5	0.3	0.5	0.5	0.3	0.4
2	P	0.5	0.8	0.5	0.8	0.3	0.5	0.8	0.8	0.8	0.5	0.8	0.8	0.8	0.8	0.7	0.8	0.8	0.8	0.8	0.6	0.6	0.8	0.8	0.8	0,8	0.8	0.8	0.8	0.8	0.8
2	R	0.4	0.4	0.4	0,4		0.4	0,4			0.4	0.5	0.5	0.7	0.5	0.5	0.5	0.5	0.5	0.7	0.5	0.5	0.5	07	0.5	0.5	0.7	0.7	0.9	0.5	07
2	T		03	0.3		0.3	0.3	0.3	0.3	0.3	0.3				0.3										0.3	0.3
2	V	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3				0.3				0.3					0.3	0.3	0.3		0.3	0.3	0.3	0.3
2	Y	0.7		0.5					0.5		0.5
3	D		0.3			0.4	0.3								0.4										0.4	0.4
3	F		0.3	0.3		0.3	0.3	0.3	0.3	0.3	0.3				0.3										0,3	0.3
3	K															0.3		0.3
3	R					0.3											0.4	0.4	0.3	0.4				0.3				0.3			0.4
3	Y	0.3	0.3	0.3	0.3		0.3	0.3			0.3	0.3	0.3	04	0.3	0.3	0.3	0.3	0.3	0.4	0.3	0.3	0.3	0,4	0.3	0.3	0.4	0.4	0.5	0.3	0.4
3	I		0.3		0.3			0.3	0.3	0.3		0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.4	0.4	0.3	0.3	0.4	0.3	0.4	0.4	0.3
3	K	0.4	0.5	0.5	0.4	0.5	0.5	0.5	0.5	0.5	0.5				0.5				0.4					0.4	0.5	0.5		04	0.4	0.4	0.4
9	L	0.3	0.3	0.3	0.3		0.3	0.3		0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3	03	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3
9	R	0.3	0.3	0.3		0.3	0.3	0.3	0.3	0.3	0.3				0.3										0.3	0.3
8	V	0.4	0.4	0.4	0.4	0.4	0.4	0.4	0.3	0.4	0.4	0.4	0.4	0.4	0.4	0.4		0.4	0.4		0.4	0.4			0.3	0.4		0.4	0.3
9	Y	0.3	0.6	0.4	0.3	0.6	0.6	0.4	0.4	0.4	0.4				0.6				0.3					0.3	0.6	0.6		0.3	0.3	0.3	0.3

Peptide-binding motifs are based on allele vectors in space Y. Only values for the Ochiai similarity index equal or greater than 0.3 are included. 'Pp' stands for amino acid position in peptide and 'Paa' for the amino acid occupying that position.

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