Skip to main content

Table 1 Threading analysis of 10 representative reductase containing sequences.

From: Molecular modeling of the reductase domain to elucidate the reaction mechanism of reduction of peptidyl thioester into its corresponding alcohol in non-ribosomal peptide synthetases

Reductase

Length

1sb8

1bkx

2hun

1db3

2b11

1kew

2pzk

1y1p

2p4h

1ek6

2c29

1udc

3gpi

2p5y

3enk

1r6d

  

341

339

329

335

294

361

310

342

310

346

324

338

273

311

340

320

Peptaibol

422

{100}

{100}

{100}

{100}

-

-

-

C

C{100}

-

-

-

-

-

C

{100}

Lys2

476

C{100}

-

C{100}

{100}

-

-

-

C

C{100}

{100}

-

-

-

-

-

C{100}

Saframycin

427

{100}

{100}

{100}

-

-

{100}

{100}

C

C{100}

-

-

-

-

C

-

C{100}

Gramicidin

421

C{100}

{100}

{100}

{100}

-

{100}

{100}

-

C{100}

-

C

-

C

-

-

C

Myxochelin

414

{100}

C

{100}

{100}

C

C

{100}

C

C{100}

-

C

{100}

-

-

-

-

Lyngbyatoxin

416

C{100}

{100}

{100}

{100}

{100}

{100}

-

C

C{100}

-

C

-

-

-

-

C{100}

Myxalamid

407

C{100}

C{100}

C

{100}

{100}

-

C

-

C

C

-

C

-

C

C

{100}

BT peptide

462

{100}

{100}

{100}

-

{100}

{100}

-

-

C{100}

{100}

-

-

-

{100}

-

C{100}

Glycopeptidolipid

358

{100}

H{100}

{100}

-

-

{100}

H

-

C{100}

-

-

-

-

-

-

C

Nostocyclopeptide

389

{100}

C

-

{100}

{100}

-

C

C

C{100}

-

-

C

C

-

-

{100}

  1. *The PDB IDs are listed for the structures that were aligned with these sequences during fold recognition analysis using the GenTHREADER and PHYRE servers. The results from GenTHREADER corresponding to confidence levels of CERTAIN and HIGH are labeled as C and H respectively. Similarly, PHYRE results corresponding to a precision level of 100% are labeled as {100}. (-) indicates the absence of a particular fold.
Back to article page

BMC Structural Biology

ISSN: 1472-6807

Contact us