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Figure 5 | BMC Structural Biology

Figure 5

From: Active site plasticity revealed from the structure of the enterobacterial N-ribohydrolase RihA bound to a competitive inhibitor

Figure 5

A comparison of the structures of the pyrimidine-preferring CU-NHs RihA and RihB from E. coli. A) Superposition of the RihA and RihB monomers, shown as Cα traces. The α9 helix conformation differs significantly between the two proteins and is indicative of the plasticity of the flexible regions in NHs to adapt to different ligands. B) Model of interactions between RihA and uridine (top) or cytidine (bottom).

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