Table 2 Heterodimeric interfaces of M protein
Interacting chains | Immature at neutral pH (3C6D) | Immature at acidic pH (3C6R) | Mature at neutral pH (1P58) |
|---|---|---|---|
DA | L56 (8.2; h), I64 (7.9; h) | T48 (4.7; m), L56 (8.1; h), I64 (5.8; m) | L128 (8.5; h), M136 (8.6; h), I161 (7.9; h), M165 (8.6; h) |
DB | - | - | - |
DC | - | - | - |
EA | - | - | - |
EB | L56 (8.2; h), I64 (7.9; h) | T48 (4.7; m), L56 (8.1; h), I64 (5.8; m) | L128 (8.5; h), M136 (8.6; h), I161 (7.9; h), M165 (8.6; h) |
EC | - | E60 (5.4; m) | E114 (6.3; h) |
FA | - | - | - |
FB | - | E60 (5.7; m) | E114 (6.3; h) |
FC | T48 (3.7; m), L56 (8.2; h), I64 (6.0; h) | T48 (4.7; m), L56 (8.1; h), I64 (5.8; m) | L128 (8.5; h), M136 (8.6; h), I161 (7.9; h), M165 (8.6; h) |