Table 2 Intramolecular interactions of ALG-2 in Ca2+/EF3-driven arginine switching loop
WT | ΔGF122 | |||
|---|---|---|---|---|
interacting atom | MF a | Ca b | Ca c | |
S120 | ||||
Hydrogen | Distance (Å) | |||
N | OK116 | 2.8 | 3.2 | 3.1 |
O | NG123/121 | 2.8 | 2.8 | NDd |
NH2R125/123 | ND | 2.8 | ND | |
OG | OL116 | 2.6 | ND | ND |
Y124/122 | ||||
hydrogen | ||||
N | OL119 | 3.1 | 3.0 | 3.0 |
OH | NE2Q159/157 | ND | ND | 2.8 |
hydrophobic | ||||
CB | CL119 | ND | 3.9 | ND |
CD1L126/124 | 3.9 | 3.7 | 3.9 | |
CGL126/124 | ND | ND | 3.7 | |
CD1 | CBF122/- | 3.7 | 3.6 | -e |
CD1L158/156 | ND | ND | 4.0 | |
CD2 | CD2L158/156 | 3.9 | ND | ND |
CE1 | CBF122/- | 3.8 | 3.8 | - |
CD1F122/- | 3.9 | ND | - | |
CD2L158/156 | 3.9 | ND | ND | |
CE2 | CGL158/156 | 3.5 | ND | ND |
CD2L158/156 | 3.7 | 3.8 | ND | |
CZ | CD1L158/156 | ND | 4.0 | ND |