Table 3 Loss of intramolecular interactions in F122A mutant
WT | F122A | ||||
|---|---|---|---|---|---|
interacting atom | MF a | Ca b | Zn c | Zn d | |
Distance (Å) | |||||
F122 | A122 | ||||
hydrogen | |||||
N | OA118 | ND | 2.9 | 3.2 | NDe |
OL119 | 3.0 | 3.1 | ND | 3.2 | |
hydrophobic | |||||
CB | CD1Y124 | 3.7 | 3.6 | 3.9 | ND |
CE1Y124 | 3.8 | 3.8 | 4.0 | ND | |
CD1 | CA118 | ND | ND | 4.0 | -f |
CAL119 | 3.9 | ND | 4.0 | - | |
CD2L119 | 3.9 | 3.7 | 4.0 | - | |
CE1Y124 | 3.9 | ND | ND | - | |
CE1 | CH2W95 | 3.9 | ND | ND | - |
CZ3W95 | 3.9 | ND | ND | - | |
CE2 | CG1V98 | ND | 4.0 | ND | - |
CZ | CH2W95 | 3.9 | ND | ND | - |
CZ3W95 | 3.5 | ND | 3.9 | - | |
CG1V98 | 3.8 | 3.5 | 3.6 | - | |