Figure 1

The pentapeptide repeats of QnrC, QnrA1 and MfpA. The characteristic pentapeptide repetitions are [A/C/S/T/V] [D/N] [L/F] [S/T/R] [G/R], highlighted in red. The conserved hydrophobic residue at the center of pentapeptide alignments is designated as i, while the residues N-terminal to the i residue are designated as i^-1 and i^-2 and the residues C-terminal to the i residue as i⁺¹ and i⁺².