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Figure 6 | BMC Structural Biology

Figure 6

From: Investigation and improvement of DNA cleavage models of polyamide + Cu(II) nuclease + OOH- ligands bound to DNA

Figure 6

Space-filling DNA model of [Cu(BPA)OOH]+/[Cu(IDB)OOH]+ binding to the minor groove of DNA and average structures of [Cu(BPA)OOH]+/[Cu(IDB)OOH]+ ligand orientating to C1'H atoms of sugars: (A), (C) for modified cyclic polyamide + [Cu(BPA)OOH]+ -d(AATATCCACCTGCA) 2 (CPDγTail-BPA) and (B), (D) for modified cyclic polyamide + [Cu(IDB)OOH]+-d(CGCTAACAGGC) 2 (CPDγTail-IDB).

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