Structural/physico-chemical properties and hydrophobicity characters of amino acid lining residues of ZmALDH2B2/RF2A tunnel-like cavity. (A) ZmALDH2B2/RF2A tunnel cavity is depicted to be spacious enough to sequester the 41 carbon chains of the polyketide T-toxin molecule (in blue) or any other molecule of such length, which fits well in the tunnel. (B) Kyte-Doolittle scale for the delineating hydrophobic character of ZmALDH2B2 protein. Regions with values above zero are hydrophobic in character. Shaded regions of the profile represent the residues of the tunnel-like cavity.