Figure 1From: Structural investigation of zymogenic and activated forms of human blood coagulation factor VIII: a computational molecular dynamics studyThe schematic representation of the sequence and domain arrangement of A) the full model of zymogen fVIII; B) the B-domainless fVIII, used in the present study; C) the activated fVIII. The functionally important calcium and copper ions bound to the inter- and intra-domains are also shown.Back to article page