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Figure 2 | BMC Structural Biology

Figure 2

From: Assessing the structural conservation of protein pockets to study functional and allosteric sites: implications for drug discovery

Figure 2

Sequence conservation. Two-dimensional histograms comparing structural and sequence conservation for pocket clusters of the different families in our data set. The left panel displays the values for pocket clusters 1 to 3 of 1,128 distinct protein families and the right panel shows the distribution for clusters containing the majority of active sites for 229 protein families. Only families with at least five representative structures are included in the analysis.

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BMC Structural Biology

ISSN: 1472-6807

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