Prediction of protein long-range contacts using an ensemble of genetic algorithm classifiers with sequence profile centers

Table 3 Performance comparison based on CASP7 evaluation

	BETApro	Distill	GPCPRED	Possum	PROFcon	SAM_T06_server	SVMcon	GaCs
Acc	19.7	13.7	10.5	21.4	8.1	18.5	13.1	20.7
Cov	3.2	1.4	2	2.6	1.6	3.9	2.8	3.1

Note that some data are extracted from Table 3 in literature [10]. The eight predictors are evaluated on the 13 CASP7 domains which can be downloaded at the CASP7 web site (http://predictioncenter.org/casp7/Casp7.html). The evaluation was based on the top L/5 predicted contacts whose corresponding residue pair separating no less than 24 residues in sequence, where L is the length of the protein chain.

ISSN: 1472-6807