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Table 1 Functions of proteins in clusters 10, 14, 15 of yeast protein network-2.0.41

From: Structural interpretation of protein-protein interaction network

Protein name Function Function type
Cluster 10
YBR160W Catalytic subunit of the main cell cycle cyclin-dependent kinase Cell cycle
YGL058W Ubiquitin-conjugating enzyme (E2), involved in postreplication repair (with Rad18p), sporulation, telomere silencing, and ubiquitin-mediated N-end rule protein degradation (with Ubr1p) Protein repair/ degradation
YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex involved in the folding of alpha-tubulin, beta-tubulin, and actin Protein folding
YOL001W Cyclin, negatively regulates phosphate metabolism Cell cycle
YPR119W B-type cyclin involved in cell cycle progression Cell cycle
(b) Cluster 14
YBR160W Catalytic subunit of the main cell cycle cyclin-dependent kinase Cell cycle
YOL001W Cyclin, negatively regulates phosphate metabolism Cell cycle
YPL153C Protein kinase, required for cell-cycle arrest in response to DNA damage Cell cycle
YML032C Stimulates strand exchange by facilitating Rad51p binding to single-stranded DNA Cell cycle
YDL020C Transcription factor that stimulates expression of proteasome genes Type Protein degradation
YGL058W Ubiquitin-conjugating enzyme (E2), involved in postreplication repair (with Rad18p), sporulation, telomere silencing, and ubiquitin-mediated N-end rule protein degradation (with Ubr1p) Protein repair/ degradation
(c) Cluster 15
YGL058W Ubiquitin-conjugating enzyme (E2), involved in postreplication repair (with Rad18p), sporulation, telomere silencing, and ubiquitin-mediated N-end rule protein degradation (with Ubr1p) Protein repair/ degradation
YBR160W Catalytic subunit of the main cell cycle cyclin-dependent kinase Cell cycle
YEL003W Subunit of the heterohexameric cochaperone prefolding complex which binds specifically to cytosolic chaperonin and transfers target proteins to it Protein folding
YDL020C Transcription factor that stimulates expression of proteasome genes Type Protein degradation
YHR200W Non-ATPase base subunit of the 19S regulatory particle (RP) of the 26S proteasome Protein degradation
YPL153C Protein kinase, required for cell-cycle arrest in response to DNA damage Cell cycle