Mining for the antibody-antigen interacting associations that predict the B cell epitopes

Zhao, Liang; Li, Jinyan

doi:10.1186/1472-6807-10-S1-S6

BMC Structural Biology

Table 4 Prediction results generated by sequence-based model and two structure-based models

From: Mining for the antibody-antigen interacting associations that predict the B cell epitopes

				Bepar			CEP			DiscoTope
PDB ID	H ¹	L ²	Ag ³	sens.	spec.	AUC	sens.	spec.	AUC	sens.	spec.	AUC
1A14	H	L	N	0.11	0.75	0.43	0.00	0.94	0.47	0.76	0.86	0.81
1AR1	C	D	B	0.27	0.89	0.58	0.13	0.85	0.49	0.00	0.89	0.45
1EO8	H	L	A	0.33	0.61	0.47	0.18	0.89	0.54	0.17	0.78	0.48
1EZV	X	Y	E	0.53	0.74	0.64	0.31	0.63	0.47	1.00	0.76	0.88
1FNS	H	L	A	0.58	0.83	0.71	0.00	0.87	0.44	0.67	0.9	0.79
1FSK	C	B	A	0.59	0.71	0.65	0.12	0.88	0.50	0.76	0.67	0.72
1G9M	H	L	G	0.33	0.75	0.54	0.18	0.88	0.53	0.08	0.79	0.44
1H0D	B	A	C	0.44	0.70	0.57	0.44	0.65	0.55	0.35	0.63	0.49
1IQD	B	A	C	0.31	0.71	0.51	0.07	0.84	0.46	0.56	0.85	0.71
1JPS	H	L	T	0.53	0.74	0.64	0.25	0.83	0.54	0.33	0.85	0.59
1JRH*	H	L	I	0.47	0.71	0.59	0.73	0.32	0.53	0.60	0.73	0.67
1LK3	H	L	A	0.39	0.71	0.55	0.17	0.87	0.52	0.61	0.84	0.73
1MHP^*	X	Y	B	0.37	0.73	0.55	0.11	0.92	0.52	0.53	0.84	0.69
1NFD	H	G	D	0.33	0.79	0.56	0.25	0.85	0.55	0.77	0.77	0.77
1NL0^*	H	L	G	0.80	0.39	0.60	0.71	0.84	0.78	0.57	0.82	0.70
1NSN^*	H	L	S	0.24	0.77	0.51	0.06	0.77	0.42	0.39	0.68	0.54
1OAZ	H	L	A	0.53	0.82	0.67	0.59	0.69	0.64	0.29	0.81	0.55
1ORS	B	A	C	0.50	0.88	0.69	0.78	0.63	0.66	0.00	0.84	0.42
1OSP	H	L	O	0.30	0.64	0.47	0.17	0.82	0.50	0.53	0.80	0.67
1PKQ^*	B	A	E	0.59	0.64	0.62	0.44	0.68	0.56	0.47	0.79	0.63
1R3J	B	A	C	0.23	0.84	0.54	0.42	0.62	0.52	0.08	0.91	0.50
1RJL^*	B	A	C	0.42	0.54	0.48	0.58	0.48	0.53	0.54	0.71	0.63
1SY6*	H	L	A	0.82	0.72	0.77	0.30	0.86	0.58	0.91	0.68	0.80
1TQB	B	C	A	0.12	0.66	0.39	0.11	0.71	0.41	0.78	0.36	0.57
1TZI^*	B	A	V	0.50	0.77	0.64	1.00	0.21	0.61	0.50	0.58	0.54
1V7M*	H	L	V	0.69	0.76	0.73	0.31	0.80	0.56	0.06	0.95	0.51
1WEJ^*	H	L	F	0.27	0.66	0.47	0.10	0.69	0.40	0.45	0.45	0.45
1YJD^*	H	L	C	0.43	0.88	0.66	0.36	0.68	0.52	0.21	0.87	0.54
1ZTX^*	H	L	E	0.25	0.72	0.49	0.75	0.34	0.55	0.19	0.88	0.54
2ADF	H	L	A	0.13	0.62	0.38	0.32	0.88	0.60	0.15	0.97	0.56
2AEP*	H	L	A	0.79	0.71	0.75	0.10	0.93	0.52	0.14	0.85	0.50
2JEL*	H	L	P	0.27	0.74	0.51	0.43	0.45	0.44	0.07	0.94	0.51

¹ Antibody heavy chain.
²Antibody light chain.
³Antigen chain.
* Fourteen non-overlapping samples.

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