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Table 4 Prediction results generated by sequence-based model and two structure-based models

From: Mining for the antibody-antigen interacting associations that predict the B cell epitopes

     Bepar CEP DiscoTope
PDB ID H 1 L 2 Ag 3 sens. spec. AUC sens. spec. AUC sens. spec. AUC
1A14 H L N 0.11 0.75 0.43 0.00 0.94 0.47 0.76 0.86 0.81
1AR1 C D B 0.27 0.89 0.58 0.13 0.85 0.49 0.00 0.89 0.45
1EO8 H L A 0.33 0.61 0.47 0.18 0.89 0.54 0.17 0.78 0.48
1EZV X Y E 0.53 0.74 0.64 0.31 0.63 0.47 1.00 0.76 0.88
1FNS H L A 0.58 0.83 0.71 0.00 0.87 0.44 0.67 0.9 0.79
1FSK C B A 0.59 0.71 0.65 0.12 0.88 0.50 0.76 0.67 0.72
1G9M H L G 0.33 0.75 0.54 0.18 0.88 0.53 0.08 0.79 0.44
1H0D B A C 0.44 0.70 0.57 0.44 0.65 0.55 0.35 0.63 0.49
1IQD B A C 0.31 0.71 0.51 0.07 0.84 0.46 0.56 0.85 0.71
1JPS H L T 0.53 0.74 0.64 0.25 0.83 0.54 0.33 0.85 0.59
1JRH* H L I 0.47 0.71 0.59 0.73 0.32 0.53 0.60 0.73 0.67
1LK3 H L A 0.39 0.71 0.55 0.17 0.87 0.52 0.61 0.84 0.73
1MHP* X Y B 0.37 0.73 0.55 0.11 0.92 0.52 0.53 0.84 0.69
1NFD H G D 0.33 0.79 0.56 0.25 0.85 0.55 0.77 0.77 0.77
1NL0* H L G 0.80 0.39 0.60 0.71 0.84 0.78 0.57 0.82 0.70
1NSN* H L S 0.24 0.77 0.51 0.06 0.77 0.42 0.39 0.68 0.54
1OAZ H L A 0.53 0.82 0.67 0.59 0.69 0.64 0.29 0.81 0.55
1ORS B A C 0.50 0.88 0.69 0.78 0.63 0.66 0.00 0.84 0.42
1OSP H L O 0.30 0.64 0.47 0.17 0.82 0.50 0.53 0.80 0.67
1PKQ* B A E 0.59 0.64 0.62 0.44 0.68 0.56 0.47 0.79 0.63
1R3J B A C 0.23 0.84 0.54 0.42 0.62 0.52 0.08 0.91 0.50
1RJL* B A C 0.42 0.54 0.48 0.58 0.48 0.53 0.54 0.71 0.63
1SY6* H L A 0.82 0.72 0.77 0.30 0.86 0.58 0.91 0.68 0.80
1TQB B C A 0.12 0.66 0.39 0.11 0.71 0.41 0.78 0.36 0.57
1TZI* B A V 0.50 0.77 0.64 1.00 0.21 0.61 0.50 0.58 0.54
1V7M* H L V 0.69 0.76 0.73 0.31 0.80 0.56 0.06 0.95 0.51
1WEJ* H L F 0.27 0.66 0.47 0.10 0.69 0.40 0.45 0.45 0.45
1YJD* H L C 0.43 0.88 0.66 0.36 0.68 0.52 0.21 0.87 0.54
1ZTX* H L E 0.25 0.72 0.49 0.75 0.34 0.55 0.19 0.88 0.54
2ADF H L A 0.13 0.62 0.38 0.32 0.88 0.60 0.15 0.97 0.56
2AEP* H L A 0.79 0.71 0.75 0.10 0.93 0.52 0.14 0.85 0.50
2JEL* H L P 0.27 0.74 0.51 0.43 0.45 0.44 0.07 0.94 0.51
  1. 1 Antibody heavy chain.
  2. 2Antibody light chain.
  3. 3Antigen chain.
  4. * Fourteen non-overlapping samples.