Table 1 Prediction of putative phosphorylation sites in human Nek6.
From: Human Nek6 is a monomeric mostly globular kinase with an unfolded short N-terminal domain
Residuea | Putative Upstream Kinaseb | Predictor (Score) |
|---|---|---|
S13 | PKA | NetPhosK (0.63) |
S14 | PKA | NetPhosK (0.52) |
S14 | Cdc2 | NetPhosK (0.53) |
S37 | PKC | NetPhosK (0.82) |
S41 | PKC | NetPhosK (0.56)/NetPhos (0.72) |
S41 | PKA | NetPhosK (0.65)/NetPhos (0.72) |
T70 | PKC | NetPhosK (0.79) |
S111 | CKII | NetPhosK (0.64) |
S131 | DNAPK | NetPhosK (0.62) |
S131 | ATM | NetPhosK (0.68) |
S158 | CKII | NetPhosK (0.53) |
S158 | Cdc2 | NetPhosK (0.51) |
T183 | PKC | NetPhosK (0.65) |
S198 | PKA | NetPhosK (0.56)/NetPhos (0.79) |
S198 | Cdc2 | NetPhosK (0.50)/NetPhos (0.79) |
S199 | CKII | NetPhosK (0.50) |
S199 | Cdc2 | NetPhosK (0.55) |
T201 | PKC | NetPhosK (0.73) |
S206 | CKI | NetPhosK (0.53)/NetPhos (0.99) |
T210 | GSK3 | NetPhosK (0.51) |
T210 | CDK5 | NetPhosK (0.55) |
S215 | GSK3 | NetPhosK (0.50)/NetPhos (0.99) |
S215 | Cdk5 | NetPhosK (0.59)/NetPhos (0.99) |
Y224 | EGFR | NetPhosK (0.55)/NetPhos (0.72) |
S232 | PKA | NetPhosK (0.67) |
S245 | p38MAPK | NetPhosK (0.50) |
S245 | Cdk5 | NetPhosK (0.55) |
S256 | CKI | NetPhosK (0.54) |
S256 | PKC | NetPhosK (0.50) |
S275 | CKII | NetPhosK (0.52) |
S311 | PKC | NetPhosK (0.66) |