Figure 5

A sequence alignment of Sa MenH and Ec MenH. Residues outlined in black are 90% conserved in 101 MenH sequences. Residues outlined in grey are conserved in Sa MenH and Ec MenH. Residues marked with a star form the catalytic triad and those residues were mutated by Jiang et al.[13] in Ec MenH are marked with a triangle. This figure was prepared using MUSCLE [42] and ALINE [43].