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Table 2 Structural novelty of MCSG structures.

From: 1,000 structures and more from the MCSG

Level of structural novelty

Number of domains (cumulative total)

Fold

54

Superfamily

66 (120)

Structural sub-group (SSG)

52 (172)

  1. Number of novel CATH structural domains solved by the MCSG. Three levels of novelty are defined: a domain with a novel fold is the first example released by the PDB of a fold in CATH (a new CAT number); a domain belonging to a novel superfamily is the first example released by the PDB of a superfamily in CATH (a new CATH number); a domain belonging to a novel structural sub-group (SSG) has a normalized RMSD of at least 5Ã… from all previously existing domains in CATH.