Skip to main content
Figure 2 | BMC Structural Biology

Figure 2

From: A new in-silico method for determination of helical transmembrane domains based on the PepLook scan: application to IL-2Rβ and IL-2Rγc receptor chains

Figure 2

Illustration of the method applied to the GpA sequence. (A) Scan of peptides with a window of 19 a.a. length, each line represents a PepLook run and its 99 structures. (B) Scan-peptides were submitted to the Impala method for membrane insertion prediction. (C) Statistical analysis showing for each residue the average of the percentage of helical structure (%), of the ASAr and of the membrane insertion (distance to the membrane in Å). These data were used to determine TMD residue at the center of the membrane.

Back to article page

BMC Structural Biology

ISSN: 1472-6807

Contact us