Figure 1

Structure and topology of the SH3 domain (a) Structure of the SH3 domain of the nephrocystine[9](PDB entry:1S1N) drawn in cartoon with β strands colored in magenta and the L28 colored in green and drawn in sticks. (b) Topology of the structure of the SH3 domain of the nephrocystine extracted from PDBsum [64]http://www.ebi.ac.uk/pdbsum/, with L28 written in green. The structure of the nph SH3 domain [9] reveals a classical β-barrel fold, surrounded by three loops: the RT loop (residues 8-23), the n-src loop (residues 30-37) and the distal hairpin (residues 41-47). This figure was produced with pymol 0.98 [10]