Figure 1From: Docking studies on novel analogues of 8 methoxy fluoroquinolones against GyrA mutants of Mycobacterium tuberculosisCommon structural features of quinolones. (A) The modifications were made at positions 3 and 7, essential for binding to DNA-gyrase complex and antibacterial spectrum respectively [20]. (B) and (C) are the chemical structures of gatifloxacin and moxifloxacin respectively.Back to article page