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Table 2 TrmI molecular volumes and cavity volumes.

From: Structural comparison of tRNA m1A58 methyltransferases revealed different molecular strategies to maintain their oligomeric architecture under extreme conditions

Organism Cavity volumesa Compactness Protein Volume (A3)
  Total cavity volumes (A 3 ) number of cavities Surface area (Å 2 ) Surface/Volume ratio (Å -1 ) Monomer a Dimer b A/B Tetramer c Δ 2 = b - 2a Δ 4 = c - 4a
M. tuberculosis 1 501 2 41130 0.39 26 460 52 970 105 900 + 50 + 60
T. thermophilus 1 182 2 39120 0.38 25 870 51 700 103 100 -40 - 380
T. maritima 2 154 3 41210 0.37 27 930 55 860 111 700 0 - 20
A. aeolicus 1 697 3 38680 0.36 27 000 53 955 107 900 - 45 - 100
P. abyssi          
3MB5 2 036 3 41880 0.38 27 420 54 820 109 600 -20 - 80
3LGA      27 330 54 635 109 200 -30 - 130
3LHD      26 440 52 840 105 700 -45 - 70
  1. a calculated for TrmI monomers without ligands