Table 4 Topomer CoMFA contour map for the R1 and R2 fragments.
Contour | Â | R1 | Â | Â | R2 | Â |
|---|---|---|---|---|---|---|
| Â | Contour level | Color | Volume estimate | Contour level | Color | Volume estimate |
Steric | -0.014 | Yellow | 14.9 | 0.000 | Yellow | 0.00 |
| Â | 0.037 | Green | 29.6 | 0.008 | Green | 9.70 |
Electrostatics | -0.014 | Blue | 19.5 | 0.000 | Blue | 0.00 |
| Â | 0.032 | Red | 9.60 | -0.004 | Red | 19.8 |