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Table 8 Statistical parameters obtained for model 7 with different atom counts.

From: In Silico Quantitative Structure-Activity Relationship Studies on P-gp Modulators of Tetrahydroisoquinoline-Ethyl-Phenylamine Series

Atom Count

N

q 2

StdErr

r 2

SEE

BHL

1-4

6

0.511

0.447

0.871

0.230

151

2-5

6

0.636

0.385

0.900

0.202

307

3-6

5

0.683

0.352

0.950

0.141

353

4-7

6

0.772

0.305

0.956

0.134

97

5-8

6

0.777

0.302

0.973

0.105

97

6-9

4

0.726

0.321

0.948

0.140

353

7-10

6

0.770

0.306

0.979

0.092

307

  1. The final model chosen for HQSAR analysis is highlighted in bold font.