Figure 3

Superimpositions of the active site of chain C in complex structures. (A) Oxy: Fd^red-CAR [(3), magenta] and Oxy: Fd^CAR [(2’), yellow]. Only the nonheme iron (sphere), waters liganded to the iron (small sphere), iron-coordinated residues (H183, H187, and D333; stick), and CAR (stick) are shown. (B) Oxy: Fd^red-CAR [(3), magenta] and OMO-O in the reduced state (PDB code 1Z02, slate) [14]. (C) Oxy: Fd^red-CAR [(3), magenta] and Oxy: Fd^red [(2), cyan]. (D) Oxy: Fd^O2 [(3’), salmon], NDO-O bound with dioxygen only (PDB code 1O7M, orange), and both oxygen and indole (PDB code 1O7N, lime) [13]. Dioxygen molecule and indole are shown as stick-and-ball and stick, respectively. (E) Oxy: Fd^CAR-O2 [(4), white], NDO-O bound with oxygen only (PDB code 1O7M, orange), and both oxygen and indole (PDB code 1O7N, lime) [13]. (F) Oxy: Fd^CAR-O2 [(4), white] and Oxy: Fd^O2 [(3’), salmon]. (G) Oxy: Fd^CAR-O2 [(4), white], Oxy: Fd^CAR [(2’), yellow], and Oxy: Fd^red-CAR [(3), magenta]. (H) Oxy: Fd^CAR-O2 [(4), white], Oxy: Fd^CAR [(2’), yellow], and Oxy: Fd^O2 [(3’), salmon].