Figure 8

Comparison of the active sites of Py Prx6•glycerol with Ap Trx•H ₂ O ₂ . A view into the active site from above shows select main chain and side chain residues of Py Prx6 (PDB: 3TB2) in dark grey (with the associated glycerol shown in purple/red). In light grey the corresponding Ap Trx (PDB: 3A2W) side chain residues are shown (with the associated H₂O₂ shown in pink/dark red to differentiate O_A and O_B). The structural alignment is derived from the alignment of the following conserved residues PxxxxTxxC_P, as was done previously [37].