Figure 1From: Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme’s active site closureNovel bisphosphonate inhibitors of human FPPS. (A) General structure of 2-aminopyridine-based bisphosphonate inhibitors (see ref. [12] for the complete list of functional groups at the substitution site). (B) Compound YS0470.Back to article page