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Table 2 The main domains and functionally active sites in the structure of CYP2E1

From: The possible mechanisms of CYP2E1 interactions with HSP90 and the influence of ethanol on them

 

Localization (residue number from N-term)

Membrane-associated domain

1-96, 368-390

Cytoplasmic domain

97-367, 391-491

Active site and its channel

41-57, 70–79, 113–119, 202–218, 298–305, 387–396, 467-471