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Figure 1 | BMC Structural Biology

Figure 1

From: Crystal structure of a new benzoic acid inhibitor of influenza neuraminidase bound with a new tilt induced by overpacking subsite C6

Figure 1

NA inhibitors. A, Zanamivir; B, oseltamivir; C, Inhibitor 1 (compound 14 of Brouillette et al. [17]); D, Inhibitor 2; E, The NA subsites that surround the transition state analog 2-deoxy-2-dehydro-N-acetylneuraminic acid (DANA). Note that in the benzoic acid series, subsite 6 is adjacent to C4 of the benzene ring. Figure made with PDB ID: 1NNB.

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BMC Structural Biology

ISSN: 1472-6807

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