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Table 1 Hydrodynamic parameters

From: Crystal structure of signal regulatory protein gamma (SIRPγ) in complex with an antibody Fab fragment

Sample

M app 0 a

S 20 , w 0 b

f f 0 app b

M calc c

S calc c

f f 0 calc c

Fab

51.2

3.7

1.4

48.4

3.81

1.22

Sirp

39.4

2.7

1.6

42.6

2.52

1.46

1:1 Complex

91.0d

4.8

1.5

91.0

4.85

1.42

2:2 Complex

Nd

Nd

Nd

182.0

7.25

1.48

  1. acalculated using SEDANAL. Units are in kilodaltons.
  2. bdetermined from sedimentation velocity. Units are in S.
  3. ccalculated from the PDB file using US-SOMO. Units are the same for the observed parameters.
  4. Nd not determined.
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BMC Structural Biology

ISSN: 1472-6807

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