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Figure 10 | BMC Structural Biology

Figure 10

From: Crosslinking and mass spectrometry suggest that the isolated NTD domain dimer of Moloney murine leukemia virus integrase adopts a parallel arrangement in solution

Figure 10

Enzyme activity assays of wild type and IN mutants. Integration assays were carried out with 7 pmol of wild type IN or 56 pmoles of IN 1–105 (or mutant K105C) and 7 pmoles of IN 106–404 for complementation assay. The products were electrophoresed on agarose gels. The upper product corresponds to non-concerted integration and the lower product to concerted integration. The substrate migrated off the gel.

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BMC Structural Biology

ISSN: 1472-6807

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