Defining structural and evolutionary modules in proteins: a community detection approach to explore sub-domain architecture

Table 3 Precision of the simulations with two modules

Sample	Intra-cluster	Intracorrelation quantiles					Intercorrelation quantiles
Size	correlation	0%	25%	50%	75%	100%	0%	25%	50%	75%	100%
	0.2	-0.12	0.112	0.178	0.247	0.532	-0.349	-0.061	0.009	0.081	0.357
	0.4	0.135	0.347	0.401	0.451	0.627	-0.372	-0.075	-0.014	0.049	0.314
100	0.6	0.405	0.581	0.617	0.653	0.758	-0.468	-0.225	-0.165	-0.104	0.116
100	0.8	0.716	0.776	0.795	0.813	0.879	-0.256	-0.087	-0.049	-0.011	0.147
	1.0	1.0	1.0	1.0	1.0	1.0	-0.018	-0.018	-0.018	-0.018	-0.018
	0.2	0.059	0.172	0.2	0.229	0.337	-0.177	-0.036	-0.008	0.023	0.151
	0.4	0.286	0.371	0.393	0.414	0.495	-0.099	0.013	0.04	0.066	0.183
500	0.6	0.516	0.587	0.602	0.618	0.67	-0.099	0.005	0.029	0.051	0.153
500	0.8	0.748	0.793	0.801	0.808	0.838	-0.069	0.014	0.031	0.05	0.131
	1.0	1.0	1.0	1.0	1.0	1.0	-0.012	-0.012	-0.012	-0.012	-0.012
	0.2	0.109	0.182	0.201	0.221	0.301	-0.116	-0.023	-0.001	0.021	0.128
	0.4	0.321	0.388	0.405	0.421	0.488	-0.133	-0.03	-0.011	0.008	0.089
1000	0.6	0.531	0.582	0.593	0.605	0.647	-0.077	-0.008	0.008	0.023	0.091
1000	0.8	0.764	0.793	0.799	0.805	0.825	-0.052	0.007	0.021	0.034	0.082
	1.0	1.0	1.0	1.0	1.0	1.0	0.026	0.026	0.026	0.026	0.026

Precision of the simulation of two modules with 100, 500 and 1000 samples. The quantiles describe the distribution of values in the lower triangle of the correlation matrix for the full simulated data set. The intercorrelation quantiles represent the distribution of the sub-matrix corresponding to the correlation between the two modules.

ISSN: 1472-6807