Figure 4

Domain organisation of Tk MAT (A) in comparison with Ec MAT (B). Tk MAT shows the same general order of sequence stretches participating in the N-terminal (red/ light pink), central (blue/ light blue) and C-terminal (cyan/ light green) domains. The additional β-sheets present in Tk MAT are highlighted in grey. The flexible helix covering the active site is shown in orange/ light orange (Tk MAT: open conformation; Ec MAT: closed conformation).