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Table 1 Mean numbers of annotation assignments per protein for eight representative annotation types

From: Quantification of the impact of PSI:Biology according to the annotations of the determined structures

    

PDB

PSI:Biology

 

PDB

PSI:Biology

 

US non-SG

Partnerships

 

US non-SG

Partnerships

Ratio of

Normalized

Normalized

Annotation type

Means

Means

Means

Means

Means

GO biological process

4.385

5.802

1.323

1.359

1.798

GO cellular component

1.889

1.765

0.934

1.327

1.239

GO molecular function

1.961

1.691

0.862

1.149

0.991

UniProt coding sequence diversity

0.369

0.741

2.008

1.299

2.609

UniProt disease

0.151

0.235

1.556

1.411

2.196

UniProt domain

0.695

1.272

1.830

1.271

2.325

UniProt ligand

1.006

0.889

0.884

1.168

1.033

UniProt PTM

1.343

1.778

1.324

2.050

2.715

Mean

  

1.340

1.379

1.863

std. err.

  

0.154

0.101

0.248

p -value

  

0.032

 

0.052

  1. The mean numbers of annotation assignments for the PDB US non-SG ensemble and the structures determined by PSI:Biology Partnerships are shown in the first two columns respectively. The third column shows the ratios of these means. The average of the eight ratios is calculated for an overall mean ratio. A 1-tailed unpaired t-test is performed to test the null hypothesis that the overall mean ratio is greater than 1 (p-value = 0.0317). In the fourth and fifth data columns, the normalized means are shown, where the normalization is done by dividing by the rates of annotation assignments by their corresponding means for the entire PDB for structures deposited during the relevant time frame (July 1, 2010 through February 28, 2013). A 1-tailed unpaired t-test is performed on the data sets to test the null hypothesis that the average of the means for PSI:Biology Partnership structures is greater than that for the PDB US non-SG ensemble (p-value = 0.0517).