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Figure 1 | BMC Structural Biology

Figure 1

From: Type I pyridoxal 5′-phosphate dependent enzymatic domains embedded within multimodular nonribosomal peptide synthetase and polyketide synthase assembly lines

Figure 1

Structurally Conserved Regions. Alignment of the Structurally Conserved Regions (SCR) of the 31 fold type I structures considered. Colors indicate conservation of residue physico-chemical properties. Each structure is labeled by its PDB code flanked by the sequence positions encompassing the reported SCRs. “SCR line” numbers the 13 conserved regions; below is the conservation histogram and the consensus sequence. The identically conserved residues in position 69 and 85 are the Asp interacting with the cofactor pyridine nitrogen and the Lys forming the Schiff base, respectively. Indels are not shown for easing the interpretation of the figure. Indel positions are denoted by the all-gap columns separating the different SCRs.

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BMC Structural Biology

ISSN: 1472-6807

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