Skip to main content
Figure 3 | BMC Structural Biology

Figure 3

From: Structural insights into Resveratrol’s antagonist and partial agonist actions on estrogen receptor alpha

Figure 3

RMSD matrices of ERα bound with different ligands computed from MD trajectory. DES-ERα, RES-ERαantagonist and ICI-ERα display highly stable initial conformation of the protein. On the contrary, RES-ERαagonist complex shows similarity with 4OHT-ERα where the initial structure changes appreciably during the simulation. RMSD matrix has been computed using trajectory analysis tools available within GROMACS packages by comparing the root mean square distances of each structure in the trajectory with respect to each other structure and generate a bi-dimentional matrix.

Back to article page