Figure 4
From: Effect of intracellular loop 3 on intrinsic dynamics of human β2-adrenergic receptor
Conformational change in the intracellular part of TM6. (A) RMSD profile of the TM6 intracellular part from its inactive and active states in the loop (red) and clipped (green) models. (B) Initial (blue) and final (yellow) snapshots from 1 μs loop trajectory, showing TM5 and TM6 in comparison with the inactive (green) and active (magenta) crystal structures. (C) Changes in the x-offset with respect to the y-offset representing the change between center of masses of ICL3 and protein’s core.