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Table 2 Residues present at positions 6.47 and 7.42-7.48

From: The role of Cysteine 6.47 in class A GPCRs

Receptor Position
6.47 7.42 7.43 7.44 7.45 7.46 7.47 7.48
β2-adrenergic C g+ G Y V N S G F
β1-adrenergic (turkey) C g+ G Y V N S A F
Dopamine D3 C g+ G Y V N S A L
Histamine H1 C g+ G Y I N S T L
Adenosine A2A C g+ S H T g+ /t N S C L
κ opioid C g+ G Y T N S S L
μ opioid (mouse) C g+ G Y T N S C L
δ opioid (mouse) C g+ G Y A N S S L
N/OFQ Opioid C g+ G Y V N S C L
Sphingosine 1-phosph. 1 C g+ A V L N S G T
CXCR4 chemokine C g+ A F F H C A L
M2 musc. ach. Tg- C Y I N S T I
M3 musc. ach. (rat) Tg- C Y I N S T V
Rhodopsin (bovine) Ct A K T g+ /t Sg- A V Y
Rhodopsin (squid) S g+ A K A St A I H
  1. Rotamer of C, S and T (g+/-: gauche+/-, t: trans) is indicated when relevant; residues involved in TM6-TM7 hydrogen bonds are displayed in bold.