BMC Structural Biology

Table 3 Occupancies of hydrophobic interactions between carbon atoms of platinum agent and near bases on DNA

From: Disturbance of DNA conformation by the binding of testosterone-based platinum drugs via groove-face and intercalative interactions: a molecular dynamics simulation study

Adducts	Ligand	DNA	Occupancy (%)
Pt(Testo)(II) + DNA	C_testosterone	C26	211.69
	C_testosterone	A27	36.08
	C_testosterone	T14	23.44
Im-Pt(Testo)(II) + DNA	C_testosterone	T12	198.67
	C_testosterone	C13	159.99
	C_testosterone	A29	41.26
	C_testosterone	G30	40.67
	C_ethyl	T14	9.12

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ISSN: 1472-6807

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