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Table 4 Percentages of occupancy times of the first three principal components during the simulations of the studied Pt + DNA adducts

From: Disturbance of DNA conformation by the binding of testosterone-based platinum drugs via groove-face and intercalative interactions: a molecular dynamics simulation study

Adducts

PC1

PC2

PC3

PCs a

Pt(Testo)(II) + DNA

68.48

20.39

4.95

93.82

Im-Pt(Testo)(II) + DNA

57.34

19.65

8.34

85.33

Pt(Py)(II) + DNA

44.31

22.42

13.88

80.61

  1. a: PCs represents sum of PC1, PC2 and PC3.
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BMC Structural Biology

ISSN: 1472-6807

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