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Figure 2 | BMC Structural Biology

Figure 2

From: Structural and functional studies of S-adenosyl-L-methionine binding proteins: a ligand-centric approach

Figure 2

Fold types of SAM-binding proteins. The folds follow SCOP classification, except for Helical Bundle, which we have assigned. A total of 18 folds include 9 Mtases and 9 non-MTases indicated by #. Structures belonging to the Rossmann fold methylases have evolved to become MTases and non- MTases and are indicated with a yellow box. SAM-dependent MTases have been previously categorized into five classes by Cheng et al.[38]. We have extended this to include a total of nine classes. The four added classes are indicated by **.

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