Medial remodeling on enolase cavities. Medial remodeling on a range of query sequences (horizontal axis) and the template. Black rectangles indicate volume of the largest fragment at the 25th percentile of this spectrum, an the top of the rectangle represents that of the 75th percentile. Colored bars indicate the volume of the largest fragment from the unmodeled query structure. Green bars indicate proteins that are sequentially nonredundant with the template, blue bars indicate proteins that are sequentially similar to the template, and red bars indicate proteins with different binding preferences.