Skip to main content

Advertisement

Figure 5 | BMC Structural Biology

Figure 5

From: A population-based evolutionary search approach to the multiple minima problem in de novo protein structure prediction

Figure 5

The distribution of lRMSDs to the native structure is shown for all the conformations in the output ensemble Ω (left) and the conformations retained in the reduced ensemble Ω p 95 . Results are combined over all 3 runs and shown for the last 3 of the 6 selected proteins (with corresponding PDB ids 1cc5, 1tig, 2ezk). The solid red line shows the distribution obtained by the simple EA with the AMW energy function, the dashed blue line shows the distribution obtained by the MEA with the AMW energy function, and the dotted green line shows the distribution obtained by the MEA with the Rosetta energy function.

Back to article page