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Figure 3 | BMC Structural Biology

Figure 3

From: A conservation and rigidity based method for detecting critical protein residues

Figure 3

Comparisons of Rigidity Analysis and Conservation Analysis against experimental data for Lysozyme. The protein's 164 residues (divided into 4 subplots for convenience) are indicated on the x-axis. The upper line (labeled 1) designates a residue as critical, and the lower line (labeled 0) designates a residue as non-critical. A red circle is drawn on the upper line to indicate that the residue is experimentally known to be critical, or on the lower line to indicate that it is experimentally known to be not critical. Blue diamonds and × s indicate whether conservation analysis or rigidity analysis, respectively, identified that residue as critical or non-critical. Residues that have a red circle, blue diamond, and × on the same line are locations for which the conservation analysis and rigidity analysis methods match the experimental data.

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