A conservation and biophysics guided stochastic approach to refining docked multimeric proteins

BMC Structural Biology

Table 1 Probability distribution table.

Conformations	Relative Probability	Selection Probability (100 conf.)	Selection Probability (2000 conf)
Top 1%	1	0.2632	0.0132
Next 2%	0.5	0.1316	0.0066
Next 7%	0.1	0.0263	0.0013
Next 20%	0.02	0.0053	0.0003
Last 70%	0.01	0.0026	0.0001

After the conformations are sorted in ascending order according to E_TC and E_TE, their selection probability depending on the number of generated conformations (100 or 2000) is assigned as described above. The relative probability is with respect to a conformation in the top 1% to be selected.

ISSN: 1472-6807