Figure 2

Conformational map of the phosphoproteome. A) Phosphorylated proteins in the PDB data set were classified under eukaryotes and prokaryotes. These were further subdivided in to subsets of conventional (Eu_S/T/Y, Pro_S/T/Y) and unconventional (Eu_H/C/D, Pro_H/C/D) phosphorylation sites. All subsets were binned with size interval of 0.1. Majority of eukaryotic conventional phosphorylation sites registered rSASA values >0.2. The rSASA values were also calculated for the single residues Ser, Thr and Tyr from phosphosite data B) and from the PDB data C).