Types of inter-atomic interactions at the MHC-peptide interface: Identifying commonality from accumulated data

BMC Structural Biology

Table 2 Class II MHC-Peptide complexes in the protein databank

MHC source	PDB code	MHC allele	Peptide sequence	Peptide length	Peptide source	Resolution (Å)
Human	1FV1	DR2	NPVVHFFKNIVTPRTPPPSQ	20	Myelin basic protein	1.90
Human	1AQD	DR1	VGSDWRFLRGYHQYA	15	Endogenous peptide	2.45
Human	1BX2	DR2	ENPVVHFFKNIVTPR	15	HMBP	2.60
Human	1A6A	DR3	PVSKMRMATPLLMQA	15	CLIP fragment	2.75
Human	1DLH	DR1	PKYVKQNTLKLAT	13	Influenza virus	2.80
Human	1SEB	DR1	AAAAAAAAAAAAA	13	Endogenous peptide	2.70
Human	1FYT	DR1	PKYVKQNTLKLAT	13	Influenza HA antigen peptide	2.60
Human	2SEB	DR4	AYMRADAAAGGA	12	Collagen II	2.50
Murine	1IAO	I-A^D	RGISQAVHAAHAEI	14	Egg ovalbumin	2.60
Murine	2IAD	I-A^D	GHATQGVTAASSHE	14	Influenza hemagglutinin	2.40

References: 1FV1 [63]; 1AQD [64]; 1BX2 [65]; 1A6A [66]; 1DLH [67]; 1SEB [68]; 1FYT [69]; 2SEB [70]; 1IAO, 2IAD [71].

ISSN: 1472-6807