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Figure 6 | BMC Structural Biology

Figure 6

From: Evolutionary connection between the catalytic subunits of DNA-dependent RNA polymerases and eukaryotic RNA-dependent RNA polymerases and the origin of RNA polymerases

Figure 6

Domain architectures of the β and β' subunits of DDRP. Domain designations: DPBB, double-psi β-barrel, SBHM, sandwich-barrel hybrid motif, ZnR, Zn-ribbon, ATL, AT-hook like, BBM, β, β'-(specific) module. βG is a domain containing a minimal version of the β grasp fold. Other designations: A, archaea, B, bacteria, E, eukaryota, Pr, Proteobacteria, Aqae, Aquifex, Spi, spirochetes, Chl, Chlamydia, Tth, Thermus thermophilus, Dra, Deinococcus radiodurans, Tma, Thermotoga maritima; Af, Archaeoglobus fulgidus, Hsp, Halobacterium sp., Mj, Methanocaldococcus jannaschii, Mth, Methanothermobacter thermoautotrophicus. Other globular regions that are conserved between the cellular DDRPs are shown by blue rectangles and non-conserved regions are shown as gray lines. Globular regions conserved in the archaeo-eukaryotic lineage are shown by red rectangles, whereas those conserved in all bacteria are shown by yellow rectangles. The proteins are not shown to scale. Splits indicated by arrows and slashes are instances when different portions of the respective subunits are encoded in separate genes.

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