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Figure 8 | BMC Structural Biology

Figure 8

From: Evolutionary connection between the catalytic subunits of DNA-dependent RNA polymerases and eukaryotic RNA-dependent RNA polymerases and the origin of RNA polymerases

Figure 8

An evolutionary scenario for the SBHM domains from the DDRP subunits and other proteins. The scenario for the derivation of various versions of the SHBM fold from the simple, ancestral 3-stranded unit was inferred from phyletic patterns, structural features and the internal duplication. The conserved basic residue present in the biotin/lipoate-binding domain-type SBHMs and the β subunit of the DDRPs is shows as a ball-and-stick model. The emergence of different lineage-specific specializations is indicated to the side of each clade.

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BMC Structural Biology

ISSN: 1472-6807

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