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Table 2 List of PKCK2 substrates, site of phosphorylation and secondary structure prediction

From: Structural basis of regulation and substrate specificity of protein kinase CK2 deduced from the modeling of protein-protein interactions

Substrate

Phosphorylation sites

Phosphorylating system (PKCK2α or holoenzyme).

PHD Result

How far from C/N termini

Ref No.

Calmodulin

S81, T79

α

Helix

Central region

7,27

NDPKA 151 aa

S122

α

Helix

~30aa away from the C-terminal

61

NAP1 DROM 370 aa

S284

α

Loop

Central region

62

 

S284

α

Loop

  

C8 of MCP 255 aa

S250

Holoenzyme

Loop

C-Terminal region

63

BTF3a 206 aa

T182

Holoenzyme

Loop

C-Terminal region (20 aa away)

64

HIV 1 Rev 116aa

S5,S8

Holoenzyme

Helix

N-Terminal region

41,42,43

PKCK2β

S 2

Holoenzyme

Loop

N-Terminal region

36