Skip to main content


Figure 5 | BMC Structural Biology

Figure 5

From: A model of tripeptidyl-peptidase I (CLN2), a ubiquitous and highly conserved member of the sedolisin family of serine-carboxyl peptidases

Figure 5

A homology-derived model of human CLN2. Ribbon diagram of the Cα trace of CLN2, with the segments that were modeled based on the highly conserved core of sedolisin and kumamolisin (r.m.s. deviation of 1 Å) colored in red. Side chains of the residues that were found to be mutated in the genes of families of patients with late-infantile neuronal ceroid lipofuscinosis [17] are marked in ball-and-stick.

Back to article page